Hrdlicka, Patrick J.: search on Z-Library

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1

Silica Nanosprings Coated with Noble Metal Nanoparticles: Highly Active SERS Substrates

Sai, V. V. R., Gangadean, Devananda, Niraula, Ishwar, Jabal, Jamie M. F., Corti, Giancarlo, McIlroy, D. N., Eric Aston, D., Branen, Josh R., Hrdlicka, Patrick J.

Journal:

The Journal of Physical Chemistry C

Year:

2011

Language:

english

File:

PDF, 8.94 MB

english, 2011

2

Optimized synthesis of LNA uracil nucleosides

T. Santhosh Kumar, Pawan Kumar, Pawan K. Sharma, Patrick J. Hrdlicka

Journal:

Tetrahedron Letters

Year:

2008

Language:

english

File:

PDF, 167 KB

english, 2008

3

Parallel RNA-strand recognition by 2′-amino-β-l-LNA

T. Santhosh Kumar, Michael E. Østergaard, Pawan K. Sharma, Poul Nielsen, Jesper Wengel, Patrick J. Hrdlicka

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 289 KB

english, 2009

4

N2′-Functionalized 2′-Amino-α-L-LNA Adenine Derivatives—Efficient Targeting of Single Stranded DNA

Andersen, Nicolai K., Wengel, Jesper, Hrdlicka, Patrick J.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2007

Language:

english

File:

PDF, 86 KB

english, 2007

5

C5-Functionalized LNA: Unparalleled Hybridization Properties and Enzymatic Stability

Michael E. Østergaard, Pawan Kumar, Bharat Baral, Daniel J. Raible, T. Santhosh Kumar, Brooke A. Anderson, Dale C. Guenther, Lee Deobald, Andrzej J. Paszczynski, Pawan K. Sharma, Patrick J. Hrdlicka

Journal:

Year:

2009

Language:

english

File:

PDF, 286 KB

english, 2009

6

Novel insights into the use of Glowing LNA as nucleic acid detection probes—Influence of labeling density and nucleobases

Michael E. Østergaard, Jyotirmoy Maity, B. Ravindra Babu, Jesper Wengel, Patrick J. Hrdlicka

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 314 KB

english, 2010

7

Carbohydrate-Functionalized Locked Nucleic Acids: Oligonucleotides with Extraordinary Binding Affinity, Target Specificity, and Enzymatic Stability

Kaura, Mamta, Guenther, Dale C., Hrdlicka, Patrick J.

Journal:

Organic Letters

Year:

2014

Language:

english

File:

PDF, 409 KB

english, 2014

8

Functionalized 2′-Amino-α-L-LNA: Directed Positioning of Intercalators for DNA Targeting

Kumar, T. Santhosh, Madsen, Andreas S., Østergaard, Michael E., Sau, Sujay P., Wengel, Jesper, Hrdlicka, Patrick J.

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 1.24 MB

english, 2009

9

Dual-Probe System Using Pyrenylmethyl-Modified Amino-Lna for Mismatch Detection

Umemoto, Tadashi, Hrdlicka, Patrick J., Babu, B. Ravindra, Wengel, Jesper

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2007

Language:

english

File:

PDF, 413 KB

english, 2007

10

Chemically modified oligonucleotides with efficient RNase H response

Birte Vester, Anne Marie Boel, Sune Lobedanz, B. Ravindra Babu, Michael Raunkjær, Dorthe Lindegaard, Raunak, Patrick J. Hrdlicka, Torben Højland, Pawan K. Sharma, Surender Kumar, Poul Nielsen, Jesper

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 551 KB

english, 2008

11

Recognition of double-stranded DNA using energetically activated duplexes with interstrand zippers of 1-, 2- or 4-pyrenyl-functionalized O2′-alkylated RNA monomers

Karmakar, Saswata, Madsen, Andreas S., Guenther, Dale C., Gibbons, Bradley C., Hrdlicka, Patrick J.

Journal:

Organic & Biomolecular Chemistry

Year:

2014

Language:

english

File:

PDF, 3.21 MB

english, 2014

12

Locked nucleic acid (LNA) induced effect on the hybridization and fluorescence properties of oligodeoxyribonucleotides modified with nucleobase-functionalized DNA monomers

Kaura, Mamta, Hrdlicka, Patrick J.

Journal:

Organic & Biomolecular Chemistry

Year:

2015

Language:

english

File:

PDF, 832 KB

english, 2015

13

Impact of non-nucleotidic bulges on recognition of mixed-sequence dsDNA by pyrene-functionalized Invader probes

Guenther, Dale C., Emehiser, Raymond G., Inskeep, Allison, Karmakar, Saswata, Hrdlicka, Patrick J.

Journal:

Organic & Biomolecular Chemistry

Year:

2020

File:

PDF, 1.49 MB

2020

14

Synthesis and biological evaluation of branched and conformationally restricted analogs of the anticancer compounds 3′-C-ethynyluridine (EUrd) and 3′-C-ethynylcytidine (ECyd)

Patrick J. Hrdlicka, Nicolai K. Andersen, Jan S. Jepsen, Flemming G. Hansen, Kim F. Haselmann, Claus Nielsen, Jesper Wengel

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 501 KB

english, 2005

15

Synthesis, nucleic acid hybridization properties and molecular modelling studies of conformationally restricted 3′-O,4′-C-methylene-linked α-l-ribonucleotides

Andreas S. Madsen, Patrick J. Hrdlicka, T. Santhosh Kumar, Jesper Wengel

Journal:

Carbohydrate Research

Year:

2006

Language:

english

File:

PDF, 240 KB

english, 2006

16

Synthesis and Hybridization Studies of 2‘-Amino-α-L-LNA and Tetracyclic “Locked LNA” †

Kumar, T. Santhosh, Madsen, Andreas S., Wengel, Jesper, Hrdlicka, Patrick J.

Journal:

Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 273 KB

english, 2006

17

Optimized DNA targeting using N,N-bis(2-pyridylmethyl)-?-alanyl 2?-amino-LNA

Babu, B. Ravindra, Hrdlicka, Patrick J., McKenzie, Christine J., Wengel, Jesper

Journal:

Chemical Communications

Year:

2005

Language:

english

File:

PDF, 313 KB

english, 2005

18

Recognition of mixed-sequence DNA using double-stranded probes with interstrand zipper arrangements of O2’-triphenylene- and coronene-functionalized RNA monomers

Karmakar, Saswata, Guenther, Dale C, Gibbons, Bradley C, Hrdlicka, Patrick J. Jerzy

Journal:

Organic & Biomolecular Chemistry

Year:

2017

Language:

english

File:

PDF, 1.27 MB

english, 2017

19

Polymerase-directed synthesis of C5-ethynyl locked nucleic acids

Rakesh N. Veedu, Harsha V. Burri, Pawan Kumar, Pawan K. Sharma, Patrick J. Hrdlicka, Birte Vester, Jesper Wengel

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 613 KB

english, 2010

20

Pyrene-functionalized triazole-linked 2′-deoxyuridines—probes for discrimination of single nucleotide polymorphisms (SNPs)

Østergaard, Michael E., Guenther, Dale C., Kumar, Pawan, Baral, Bharat, Deobald, Lee, Paszczynski, Andrzej J., Sharma, Pawan K., Hrdlicka, Patrick J.

Journal:

Chemical Communications

Year:

2010

Language:

english

File:

PDF, 1.03 MB

english, 2010

21

Recognition of Mixed-Sequence DNA Duplexes: Design Guidelines for Invaders Based on 2′- O -(Pyren-1-yl)methyl-RNA Monomers

Karmakar, Saswata, Guenther, Dale C., Hrdlicka, Patrick J.

Journal:

Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 1.38 MB

english, 2013

22

Invader LNA: Efficient targeting of short double stranded DNA

Sau, Sujay P., Kumar, T. Santhosh, Hrdlicka, Patrick J.

Journal:

Organic & Biomolecular Chemistry

Year:

2010

Language:

english

File:

PDF, 291 KB

english, 2010

23

C5-Amino acid functionalized LNA: positively poised for antisense applications

Guenther, Dale C., Kumar, Pawan, Anderson, Brooke A., Hrdlicka, Patrick J.

Journal:

Chemical Communications

Year:

2014

Language:

english

File:

PDF, 1.12 MB

english, 2014

24

Hybridization Study of PNA-DNA in the Solution and Surface-Solution Interface for Biosensor Application

Rastogi, Shiva K., Mishra, Nirankar N., Østergaard, Michael E., Cameron, Eric, Finaloski, Brian, Hrdlicka, Patrick J., Maki, Wusi C.

Journal:

Analytical Letters

Year:

2009

Language:

english

File:

PDF, 999 KB

english, 2009

25

Increased duplex stabilization in porphyrin-LNA zipper arrays with structure dependent exciton coupling

Stulz, Eugen, Hrdlicka, Patrick Jerzy, Hussain, Rohanah, Siligardi, Giuliano, Berova, Nina, Singleton, Daniel G, Kumar, Pawan

Journal:

Organic & Biomolecular Chemistry

Year:

2015

Language:

english

File:

PDF, 994 KB

english, 2015

26

Characterization of Nerolidol Biotransformation Based on Indirect On-Line Estimation of Biomass Concentration and Physiological State in Batch Cultures of Aspergillus niger

Patrick J. Hrdlicka, Anders B. Sørensen, Bjarne R. Poulsen, George J. G. Ruijter, Jaap Visser, Jens J. L. Iversen

Journal:

Biotechnology Progress

Year:

2004

Language:

english

File:

PDF, 155 KB

english, 2004

27

Glowing Locked Nucleic Acids: Brightly Fluorescent Probes for Detection of Nucleic Acids in Cells

Østergaard, Michael E., Cheguru, Pallavi, Papasani, Madhusudhan R., Hill, Rodney A., Hrdlicka, Patrick J.

Journal:

Journal of the American Chemical Society

Year:

2010

Language:

english

File:

PDF, 341 KB

english, 2010

28

Invaders: Recognition of Double-Stranded DNA by Using Duplexes Modified with Interstrand Zippers of 2′- O -(Pyren-1-yl)methyl-ribonucleotides

Didion, Bradley A., Karmakar, Saswata, Guenther, Dale C., Sau, Sujay P., Verstegen, John P., Hrdlicka, Patrick J.

Journal:

Year:

2013

Language:

english

File:

PDF, 787 KB

english, 2013

29

High-Affinity DNA Targeting Using Readily Accessible Mimics of N2′-Functionalized 2′-Amino-α-L-LNA

Karmakar, Saswata, Anderson, Brooke A., Rathje, Rie L., Andersen, Sanne, Jensen, Troels B., Nielsen, Poul, Hrdlicka, Patrick J.

Journal:

Journal of Organic Chemistry

Year:

2011

Language:

english

File:

PDF, 1.68 MB

english, 2011

30

Invader probes: harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications

Guenther, Dale C., Anderson, Grace H., Karmakar, Saswata, Anderson, Brooke A., Didion, Bradley A., Guo, Wei, Verstegen, John P., Hrdlicka, Patrick J.

Journal:

Chemical Science

Year:

2015

Language:

english

File:

PDF, 1.95 MB

english, 2015

31

Head-to-head comparison of LNA, MP γPNA, INA and Invader probes targeting mixed-sequence double-stranded DNA

Emehiser, Raymond G., Hall, Eric, Guenther, Dale C., Karmakar, Saswata, Hrdlicka, Patrick J.

Journal:

Organic & Biomolecular Chemistry

Year:

2020

File:

PDF, 2.68 MB

2020

32

Mixed-Sequence Recognition of Double-Stranded DNA Using Enzymatically Stable Phosphorothioate Invader Probes

Anderson, Brooke, Karmakar, Saswata, Hrdlicka, Patrick

Journal:

Year:

2015

Language:

english

File:

PDF, 2.30 MB

english, 2015

33

Modified Nucleosides in Biochemistry, Biotechnology and Medicine. Edited by Piet Herdewijn.

Patrick J. Hrdlicka

Journal:

Year:

2009

Language:

english

File:

PDF, 145 KB

english, 2009

34

DNA detection on lateral flow test strips: enhanced signal sensitivity using LNA-conjugated gold nanoparticles

Rastogi, Shiva K., Gibson, CharLene M., Branen, Josh R., Eric Aston, D., Larry Branen, A., Hrdlicka, Patrick J.

Journal:

Chemical Communications

Year:

2012

Language:

english

File:

PDF, 1.48 MB

english, 2012

35

Self-Assembled Monolayers of Thiols Adsorbed on Au/ZnO-Functionalized Silica Nanosprings: Photoelectron Spectroscopy-Analysis and Detection of Vaporized Explosives

Fouetio Kengne, Blaise-Alexis, Karmakar, Saswata, Kaura, Mamta, Sai, V.V.R., Corti, Giancarlo, Niraula, Ishwar B., Larin, Alexander, Hall, Jessica, Sowell, Dewayne, Hrdlicka, Patrick J., Dobrokhotov,

Journal:

ACS Applied Materials & Interfaces

Year:

2014

Language:

english

File:

PDF, 4.29 MB

english, 2014

36

Optimized DNA-targeting using triplex forming C5-alkynyl functionalized LNA

Sau, Sujay P., Kumar, Pawan, Anderson, Brooke A., Østergaard, Michael E., Deobald, Lee, Paszczynski, Andrzej, Sharma, Pawan K., Hrdlicka, Patrick J.

Journal:

Chemical Communications

Year:

2009

Language:

english

File:

PDF, 980 KB

english, 2009

37

Recognition of Double-Stranded DNA Using Energetically Activated Duplexes Modified with N2′-Pyrene-, Perylene-, or Coronene-Functionalized 2′- N -Methyl-2′-amino-DNA Monomers

Anderson, Brooke A., Onley, Jared J., Hrdlicka, Patrick J.

Journal:

Journal of Organic Chemistry

Year:

2015

Language:

english

File:

PDF, 2.66 MB

english, 2015

38

Novel nucleic acid architectures involving locked nucleic acid (LNA) and pyrene residues: Results from an Indo-Danish collaboration

Babu, B. Ravindra, Raunak,, Sørensen, Mads D., Hrdlicka, Patrick J., Trikha, Smriti, Prasad, Ashok K., Parmar, Virinder S., Wengel, Jesper

Journal:

Pure & Applied Chemistry

Year:

2005

File:

PDF, 257 KB

2005

39

Efficient Discrimination of Single Nucleotide Polymorphisms (SNPs) Using Oligonucleotides Modified with C5-Pyrene-Functionalized DNA and Flanking Locked Nucleic Acid (LNA) Monomers

Kaura, Mamta, Hrdlicka, Patrick J.

Journal:

Chemistry – An Asian Journal

Year:

2016

Language:

english

File:

PDF, 735 KB

english, 2016

40

Synthesis and biological evaluation of nucleobase-modified analogs of the anticancer compounds 3′-C-ethynyluridine (EUrd) and 3′-C-ethynylcytidine (ECyd)

Patrick J. Hrdlicka, Jan S. Jepsen, Claus Nielsen, Jesper Wengel

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 241 KB

english, 2005

41

Merging two strategies for mixed-sequence recognition of double-stranded DNA: Pseudocomplementary Invader probes.

Anderson, Brooke A, Hrdlicka, Patrick J.

Journal:

Journal of Organic Chemistry

Year:

2016

Language:

english

File:

PDF, 2.04 MB

english, 2016

42

Recognition of mixed-sequence DNA targets using spermine-modified Invader probes

Adhikari, Shiva P, Emehiser, Raymond, Karmakar, Saswata, Hrdlicka, Patrick J.

Journal:

Organic & Biomolecular Chemistry

Year:

2019

Language:

english

File:

PDF, 2.73 MB

english, 2019

43

Pyrene-functionalized oligonucleotides and locked nucleic acids (LNAs): Tools for fundamental research, diagnostics, and nanotechnology

Østergaard, Michael E., Hrdlicka, Patrick J.

Journal:

Chemical Society Reviews

Year:

2011

Language:

english

File:

PDF, 4.65 MB

english, 2011

44

DNA strands with alternating incorporations of LNA and 2′-O-(pyren-1-yl)methyluridine: SNP-discriminating RNA detection probes

Karmakar, Saswata, Hrdlicka, Patrick J.

Journal:

Chemical Science

Year:

2013

Language:

english

File:

PDF, 460 KB

english, 2013

45

Nucleic Acid Structural Engineering Using Pyrene-Functionalized 2′-Amino-α-L-LNA Monomers and Abasic Sites

Kumar, T. Santhosh, Madsen, Andreas S., Østergaard, Michael E., Wengel, Jesper, Hrdlicka, Patrick J.

Journal:

Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 459 KB

english, 2008

46

Sandwich assay for mixed-sequence recognition of double-stranded DNA: Invader-based detection of targets specific to foodborne pathogens

Denn, Benjamin, Karmakar, Saswata, Guenther, Dale C., Hrdlicka, Patrick J.

Journal:

Chemical Communications

Year:

2013

Language:

english

File:

PDF, 1.21 MB

english, 2013

47

Novel nucleic acid architectures involving locked nucleic acid (LNA) and pyrene residues: Results from an Indo-Danish collaboration

Babu, B. Ravindra, Raunak,, Sørensen, Mads D., Hrdlicka, Patrick J., Trikha, Smriti, Prasad, Ashok K., Parmar, Virinder S., Wengel, Jesper

Journal:

Pure & Applied Chemistry

Year:

2005

Language:

english

File:

PDF, 257 KB

english, 2005

48

Synthesis and Characterization of Oligodeoxyribonucleotides Modified with 2′-Amino-α- l -LNA Adenine Monomers: High-Affinity Targeting of Single-Stranded DNA

Andersen, Nicolai K., Anderson, Brooke A., Wengel, Jesper, Hrdlicka, Patrick J.

Journal:

Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 972 KB

english, 2013

49

C5-Alkynyl-Functionalized α-L-LNA: Synthesis, Thermal Denaturation Experiments and Enzymatic Stability

Kumar, Pawan, Baral, Bharat, Anderson, Brooke A., Guenther, Dale C., Østergaard, Michael E., Sharma, Pawan K., Hrdlicka, Patrick J.

Journal:

Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 1.09 MB

english, 2014

50

Synthesis and Biophysical Properties of C5-Functionalized LNA (Locked Nucleic Acid)

Kumar, Pawan, Østergaard, Michael E., Baral, Bharat, Anderson, Brooke A., Guenther, Dale C., Kaura, Mamta, Raible, Daniel J., Sharma, Pawan K., Hrdlicka, Patrick J.

Journal:

Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 1.35 MB

english, 2014

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